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<p style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="color:#3498db;"><strong><a href="http://www.india-drugstore.com/p/wenda_detail.php?id=2111&art_cate_value=0&art_navid_value=2"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="background-color:#f1c40f;">塞尔帕替尼（赛普替尼-292）：</span></span></span></span></span></span></a></strong></span></p>

<p style="text-align:left; margin:0cm 0cm 0.0001pt"> </p>

<p style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">对于初步诊断且未经过任何治疗的RET融合阳性NSCLC患者，接受治疗后肿瘤体积缩小≥30%的患者比例高达84%，且疗效持久。</span></span></span></span></span></span></span></p>

<ul>
	<li align="left" style="margin-top:4.5pt; margin-right:0cm; margin-bottom:.0001pt; text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">对于之前接受过系统性铂类化疗的RET融合阳性NSCLC患者，同样表现出高疗效，肿瘤体积缩小≥30%的患者比例达到70%。</span></span></span></span></span></span></span></li>
	<li style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="color:#05073b"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif"">适应症：主要用于治疗具有RET基因融合的晚期或转移性非小细胞肺癌（NSCLC）和甲状腺髓样癌（MTC）患者。</span></span></span></span></span></span></span></li>
	<li style="margin-top:4.5pt; text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="color:#05073b"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif"">用药方案：根据患者的体重调整剂量，每日口服两次（12小时一次）。体重小于50kg的患者每次剂量为120mg，体重达到或超过50kg的患者每次剂量为160mg。</span></span></span></span></span></span></span></li>
	<li style="margin-top:4.5pt; text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="color:#05073b"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif"">特性：作为可逆性靶向药物，专注于RET激酶，通过精准抑制其活性来阻断下游信号传导。</span></span></span></span></span></span></span></li>
</ul>

<p align="left" style="margin-top:4.5pt; text-align:left; margin:0cm 0cm 0.0001pt"> </p>

<p align="left" style="margin-top:4.5pt; text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">印度大药房可以购买到292-塞尔帕替尼（赛普替尼）</span></span></span></span></span></span></p>

<p align="left" style="margin-top:4.5pt; text-align:left; margin:0cm 0cm 0.0001pt"> </p>

<p align="left" style="margin-top:4.5pt; text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b"><img alt="" src="../upload/66ebf01a258f3619061967.jpg" style="width: 270px; height: 400px;" /></span></span></span></span></span></span></p>

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