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<h3 style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:left"><span style="color:#3498db;"><strong><span style="font-size:13.5pt"><span style="background:#ffffff"><span style="font-family:宋体"><span style="font-weight:bold"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="letter-spacing:0.0000pt"><span style="font-weight:bold"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑"><span style="background-color:#f1c40f;"><a href="http://www.india-drugstore.com/p/zhuanti_detail.php?id=1853">塞普替尼，塞尔帕替尼selpercatinib</a></span></font></span></span></span></span></span></span></span></span></span></span></span></strong></span><a href="http://www.india-drugstore.com/p/zhuanti_detail.php?id=1853"><span style="color:#3498db;"><strong><span style="font-size:13.5pt"><span style="background:#ffffff"><span style="font-family:宋体"><span style="font-weight:bold"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="letter-spacing:0.0000pt"><span style="font-weight:bold"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑"><span style="background-color:#f1c40f;"> </span></font></span></span></span></span></span></span></span></span></span></span></span></strong></span></a><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">储存在20°C至25°C(68°F至77°F); 允许短期储存于15°C到30°C(59°F到86°F)之间。</font></span></span></span></span></span></span></span></span></span></h3>

<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">塞尔帕替尼目前有老挝第二制药厂的和孟加拉珠峰药厂的，价格比较适中，上市时间都比较长了。</font></span></span></span></span></span></span></span></span></span></p>

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<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">塞尔帕替尼是继今年</font><font face="微软雅黑">3月普拉替尼(pralsetinib,BLU-667)获批用于既往接受过含铂化疗的RET基因融合阳性的局部晚期或转移性NSCLC成人患者的治疗后有望第二个上市的RET 抑制剂，且适应症更广。</font></span></span></span></span></span></span></span></span></span></p>

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<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">塞尔帕替尼用于治疗晚期</font><font face="微软雅黑">RET融合阳性非小细胞</font></span></span></span></span></span></span></span><a href="https://www.cancer123.com/types/lung-cancer/"><span class="15" style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">肺癌</font></span></span></span></span></span></span></span></a><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">(NSCLC)患者、RET融合阳性</font></span></span></span></span></span></span></span><a href="https://www.cancer123.com/types/thyroid-cancer/"><span class="15" style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">甲状腺癌</font></span></span></span></span></span></span></span></a><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">患者、</font><font face="微软雅黑">RET突变型甲状腺髓样癌(MTC)患者。该药是2020年在美国上市的，塞尔帕替尼治疗曾接受过铂类化疗的RET融合阳性非小细胞</font></span></span></span></span></span></span></span><a href="https://www.cancer123.com/types/lung-cancer/"><span class="15" style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">肺癌</font></span></span></span></span></span></span></span></a><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">患者，</font><font face="微软雅黑">81%的患者缓解持续时间超过6个月，整体缓解率达到64%。</font></span></span></span></span></span></span></span></span></span></p>

<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑"><img alt="" src="../upload/64facb970cc04674338819.jpg" style="width: 405px; height: 600px;" /></font></span></span></span></span></span></span></span></span></span></p>

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