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<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><a href="http://www.india-drugstore.com/p/story_detail.php?id=2012&art_cate_value=0&art_navid_value=2"><span style="color:#3498db;"><strong><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑"><span style="background-color:#f1c40f;">卡马替尼</span></font></span></span></span></span></span></span></strong></span></a><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">适应症：</font></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">用于治疗转移性非小细胞</font></span></span></span></span></span></span></span><a href="https://www.cancer123.com/types/lung-cancer/"><span class="15" style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">肺癌</font></span></span></span></span></span></span></span></a><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">(NSCLC)的成年患者，其肿瘤突变导致间充质-上皮转化(MET)外显子14跳跃。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">用法用量：</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　推荐剂量为每日两次口服</font><font face="微软雅黑">400mg,饭前或饭后均可。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　整片吞下，请勿打碎、压碎或咀嚼药片。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">不良反应：</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">最常见的不良反应</font><font face="微软雅黑">(≥20%)为周围水肿，恶心，疲劳，呕吐，呼吸困难和食欲下降。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"> </p>

<p style="margin:0pt 0pt 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">卡马替尼是一种激酶抑制剂，适用于治疗转移性非小细胞</font></span></span></span></span></span></span></span><a href="https://www.cancer123.com/types/lung-cancer/"><span class="15" style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">肺癌</font></span></span></span></span></span></span></span></a><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">(NSCLC)的成年患者，该患者的突变具有导致间充质-上皮转化(MET)外显子14跳变的现象，这是通过FDA批准的测试所检测到的。</font></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"> </p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">贮藏：</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　用干燥剂盒分配原包装。存放在</font><font face="微软雅黑">20°C至25°C(68°F至77°F)，允许偏移在15°C至30°C(59°F至86°F)之间。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　防潮。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑">　　首次打开瓶子</font><font face="微软雅黑">6周后，请丢弃所有剩余的未使用的TABRECTA。</font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"><span style="font-size:12pt"><span style="background:#ffffff"><span style="text-justify:inter-ideograph"><span style="line-height:12.0000pt"><span style="font-family:Calibri"><span style="font-size:12.0000pt"><span style="background:#ffffff"><span style="font-family:微软雅黑"><span style="color:#000000"><span style="letter-spacing:0.0000pt"><span style="text-transform:none"><span style="font-style:normal"><font face="微软雅黑"><img alt="" src="../upload/655f17db72859548918507.jpg" style="width: 200px; height: 166px;" /></font></span></span></span></span></span></span></span></span></span></span></span></span></p>

<p align="justify" class="p" style="margin-top:0.0000pt; margin-right:0.0000pt; margin-bottom:0.0000pt; margin-left:0.0000pt; padding:0pt 0pt 0pt 0pt ; text-align:justify; margin:5pt 0pt"> </p>

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