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<p style="margin:0cm 0cm 0.0001pt; text-align:justify"><strong><span style="font-size:10.5pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="background:#fdfdfe"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#3498db;"><span style="background-color:#f1c40f;">赛普替尼</span></span><span style="color:#05073b"><span style="font-variant-ligatures:normal; -webkit-text-stroke-width:0px"><span style="font-variant-caps:normal"><span style="orphans:2"><span style="widows:2"><span style="text-decoration-thickness:initial"><span style="text-decoration-style:initial"><span style="text-decoration-color:initial"><span style="float:none"><span style="word-spacing:0px">：</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></strong></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"> </p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="background:#fdfdfe"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">主要用于治疗转移性RET融合阳性的非小细胞肺癌（NSCLC）成人患者，以及需要全身治疗的晚期或转移性RET突变甲状腺髓样癌的成人和12岁以上儿童患者。此外，还适用于需要全身治疗且放射碘治疗抵抗的晚期或转移性RET融合阳性甲状腺癌的成人和12岁以上儿童患者。</span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"> </p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri,"sans-serif""><strong><span style="font-size:12.0pt"><span style="background:#fdfdfe"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">普拉替尼：</span></span></span></span></strong></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"> </p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="background:#fdfdfe"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">主要用于治疗转染重排（RET）基因融合阳性的局部晚期或转移性非小细胞肺癌（NSCLC）成人患者，以及需要系统性治疗的晚期或转移性RET突变型甲状腺髓样癌（MTC）成人和12岁及以上儿童患者，还有需要系统性治疗且放射性碘难治（如果放射性碘适用）的晚期或转移性RET融合阳性甲状腺癌成人和12岁及以上儿童患者。</span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"> </p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"><span style="font-size:10.5pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="background:#fdfdfe"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">病人如何做选择呢？</span></span></span></span></span></span></p>

<p style="margin:0cm 0cm 0.0001pt; text-align:justify"> </p>

<ol>
	<li align="left" style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">根据基因检测结果</span></span></span></b><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">：确保患者已明确检测出RET基因的融合阳性状态。</span></span></span></span></span></span></span></li>
	<li align="left" style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">综合考虑病情</span></span></span></b><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">：根据患者的具体病情、疾病分期、身体状况等因素进行选择。</span></span></span></span></span></span></span></li>
	<li align="left" style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><b><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">咨询专业医生</span></span></span></b><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b">：与医生进行充分沟通，了解药物的适应症、疗效、安全性及患者的耐受性等信息，制定个性化的治疗方案。</span></span></span></span></span></span></span></li>
</ol>

<p style="text-align:left; margin:0cm 0cm 0.0001pt"> </p>

<p style="text-align:left; margin:0cm 0cm 0.0001pt"><span style="font-size:10.5pt"><span style="background:#fdfdfe"><span style="tab-stops:list 36.0pt"><span style="font-family:Calibri,"sans-serif""><span style="font-size:12.0pt"><span style="font-family:"微软雅黑","sans-serif""><span style="color:#05073b"><img alt="" src="../upload/66ebed60758f0441162857.jpg" style="width: 270px; height: 400px;" /></span></span></span></span></span></span></span></p>

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